Introduction to Molecular Biology of RNA

David Elliott; Michael Ladomery · 2015

This chapter provides an overview of the biochemical properties of RNA, including the versatility of its structure that enables a multitude of RNA molecules and functions in cells.

Tür:
Kitap Bölümü
Yazar:
David Elliott; Michael Ladomery
Yayın yılı:
2015
Yayıncı:
Oxford University Press
Dil:
en

This chapter provides an overview of the biochemical properties of RNA, including the versatility of its structure that enables a multitude of RNA molecules and functions in cells. It describes different types of RNA-binding domains that have evolved, and the co-transcriptional processes of capping and pre-mRNA splicing, cleavage, and polyadenylation. It also discusses the process of alternative splicing, which is a major generator of proteomic diversity. The chapter covers the processes of RNA editing, nucleocytoplasmic traffic, mRNA localization, translation, stability, decay, and rRNA and tRNA processing. It also gives a historical perspective in explaining the roles of pioneering scientists in some of the key discoveries in molecular biology.

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This chapter provides an overview of the biochemical properties of RNA, including the versatility of its structure that enables a multitude of RNA molecules and functions in cells.
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David Elliott; Michael Ladomery